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    A next step for the investigating team is to examine the accuracy of the technology in quantifying the effect of various medications in the active fat content of the human body. (2018): Non-invasive Measurement of Brown Fat Metabolism Based on Optoacoustic Imaging of Hemoglobin Gradients.

    Further Information Original Publication: Reber, J. Cell Metabolism, DOI: 10.1016/20 As German Research Center for Environmental Health, Helmholtz Zentrum München pursues the goal of developing personalized medical approaches for the prevention and therapy of major common diseases such as diabetes mellitus and lung diseases.

    “Overall we expect MSOT to become a key tool in measuring metabolic parameters in tissue, using portable and safe MSOT technology” notes Ntziachristos.

    He adds: “This ability can revolutionize understanding of metabolic processes not only in patients but also in healthy individuals.” "The higher metabolic demand of the brown adipose tissue is supplied by increased blood circulation and oxygen utilization, which can be made visible in the tissue and the venous outflow by MSOT” explains Professor Martin Klingenspor from the Chair for Molecular Nutritional Medicine.

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    This light is absorbed by tissues containing hemoglobin causing them to minimally warm up and transiently expand.

    This expansion creates sound waves which can be measured." The study demonstrates a direct relationship between the metabolic activation of the brown adipose tissue measured using hemoglobin gradients as an intrinsic biomarker of tissue metabolism and its calorie consumption after stimulation.

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