Following appearances in television movies and a commercial for Kool-Aid, at 13 she landed the role of Darlene Conner, the sarcastic middle child, in Roseanne.Sara was a cast member in the show's nine-year run (1988–97), for which she wrote a fourth-season episode story (the teleplay was written by the Guild Writers for the show) called "Don't Make Me Over".It was announced on April 28, 2017 that Gilbert along with most of the original cast would be returning for an eight episode revival series of Roseanne. Due to the revival’s strong ratings and positive critical reception, it was renewed for another season.However, on May 29, 2018, in the wake of racist remarks made by Barr on Twitter regarding Valerie Jarrett (an advisor of former president Barack Obama), ABC cancelled the revival after a single season.Her maternal grandfather is The Honeymooners creator Harry Crane. Her two siblings on her mother's side, Melissa Gilbert and Jonathan Gilbert, were stars of Little House on the Prairie.In 1984, Sara took the last name Gilbert for Paul Gilbert, her mother's first husband.
She also had a recurring role on the short-lived CBS sitcom The Class as Fern Velch.Sara Gilbert has been very open about her sexuality in recent years, but there was a time early on in her career when she wasn't quite as comfortable letting people know who she really was."And I thought he was super cute and had a total crush on him, and we started dating, and he would come over, and we would make out, and then I would start to get depressed."She continued: "Johnny felt badly, I think, and started to take it personally and didn't know what was going on.She took the role in TV series “Roseanne” as Darlene in 1988 which was the most watched TV show in 1989-1990 and made Sara Gilbert a teen superstar.At the same time she graduated from the university and took some other roles in television shows.From 2007 to 2010, Gilbert appeared in episodes of the CBS TV series The Big Bang Theory as Leslie Winkle, a scientist friend of Leonard Hofstadter played by Johnny Galecki, who had previously played Gilbert's love interest David Healy on Roseanne.In the second episode of the second season of The Big Bang Theory, Gilbert was elevated to the show's main cast, portraying again a potential love interest of Galecki's character, and at one point a love interest to Howard Wolowitz (Simon Helberg).(Each of the show's co-hosts are sharing confessions as part of a secret-spilling week; prior to Gilbert's revelation, Julie Chen admitted to having plastic surgery in order to make her "Asian eyes" look bigger.)PHOTOS: Out and proud celebs"So, some of you may know that when I was a teenager, I dated Johnny Galecki for a little while, who played my boyfriend and husband on ," Gilbert began.So I eventually told him that I thought it was about my sexuality and he was super sweet about it."PHOTOS: Hollywood's gay power couples(He's still super sweet.In 2000, Gilbert appeared in a production of "The Hot L Baltimore" as part of the Williamstown (Mass.) theater festival.As a teenager, Gilbert dated her Roseanne (and later The Big Bang Theory) co-star Johnny Galecki (their characters also dated).Sara wanted to play so hard that she did everything to become famous and start acting professionally.Firstly, Sara started doing advertisements and later she got into TV specials: “Calamity Jane”, “ABC Weekend Special: Runaway Ralph”.Gilbert appeared in two films alongside Drew Barrymore, in Poison Ivy in 1992 and Riding In Cars With Boys in 2001.